The 2025 men’s NCAA tournament is brimming with anticipation as the first round approaches, promising a slew of potential upsets that could make or break brackets. With double-digit seeds looking stronger than ever and the battle lines drawn, here’s a closer look at five matchups that could witness the underdogs overthrowing the favorites.
McNeese vs. Clemson: An Unpredictable Clash
Set to tip off at 2:15 p.m. on Thursday, the game between No. 12 McNeese and No. 5 Clemson is poised to deliver early tournament drama. McNeese, rebounding from a first-round exit at the hands of Gonzaga last year, showcases a well-rounded team with six players averaging near double figures. Under the leadership of Will Wade, the Cowboys boast a top-20 turnover rate and an effective field goal defense that places them 39th nationwide. Clemson, on the other hand, struggles with defensive rebounding, a vulnerability McNeese is prepared to exploit.
BYU vs. VCU: A Defensive Showdown
Scheduled for a 3:05 p.m. start on the same Thursday, No. 11 VCU faces No. 6 BYU in a game that’s too close to call. VCU, having dominated the Atlantic 10, brings the nation’s top defensive metrics against a BYU team known for its offensive prowess. The Rams’ ability to disrupt BYU’s flow and challenge shooter Egor Demin could be key. BYU’s task is to manage their turnovers and capitalize on their offensive strengths to overcome VCU’s stringent defense.
Drake vs. Missouri: A Battle of Contrasts
Drake, the Missouri Valley Conference champion, takes on a struggling Missouri team at 6:35 p.m. Thursday. Missouri’s defensive lapses have been costly, often overshadowing their offensive capabilities. Drake, with standout guard Bennett Stirtz, has momentum, having won 18 of their last 19 games. The contrasting styles—Drake’s slow pace vs. Missouri’s fast-paced games—will be fascinating to watch as each team tries to impose its rhythm.
UC San Diego vs. Michigan: Analytical Underdog Meets Historical Power
The late game on Thursday at 9:00 p.m. sees No. 12 UC San Diego challenging No. 5 Michigan. The Tritons, led by Aniwaniwa Tait-Jones, have excelled in minimizing turnovers and maximizing shot efficiency. Michigan, needing to control the ball better, faces a crucial test against UC San Diego’s aggressive defense. The size mismatch could be Michigan’s advantage, but UC San Diego’s dynamic playstyle and offensive efficiency pose a significant threat.
Colorado State vs. Memphis: The Favorite Underdog
Finally, at 1:00 p.m. on Friday, No. 12 Colorado State goes up against No. 5 Memphis in a matchup where the underdog might not be so under the radar. Colorado State, riding a ten-game winning streak, features Nique Clifford, who’s been phenomenal this season. Memphis, while strong, has been inconsistent, particularly in games against lower-tier conference teams. The Rams’ efficient shooting and balanced attack could very well lead to a victory over Memphis.
Each of these games encapsulates the unpredictability and excitement of March Madness. Whether it’s the strategic matchups, standout individual performances, or the sheer thrill of potential bracket-busters, the first round of the 2025 NCAA tournament is not to be missed. Fans and bracketologists alike should keep an eye on these critical games as they unfold, potentially reshaping expectations and paving the way for new contenders to emerge on the national stage.
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